The Role of AutoDock and Related Techniques in Bioinformatics for Developing Immune Proteins and Therapeutic Treatments

Abstract

The field of computational biology has revolutionized drug discovery and protein engineering through sophisticated molecular docking techniques. AutoDock, a suite of automated docking tools, has emerged as a cornerstone technology in bioinformatics for developing immune proteins, modified antibiotics, and vaccine candidates. This comprehensive review examines the applications, methodologies, and recent advancements in AutoDock and related computational approaches for therapeutic development. The integration of molecular docking with immunoinformatics has enabled the rational design of multi-epitope vaccines, optimization of protein-ligand interactions, and development of novel therapeutic compounds. Current research demonstrates the effectiveness of these computational approaches in accelerating drug discovery pipelines while reducing experimental costs and time requirements.